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Identification of GPR83 as the receptor for the neuroendocrine peptide PEN
PEN is an abundant peptide in the brain that has been implicated in the regulation of feeding. We identified a receptor for PEN in mouse hypothalamus and Neuro2A cells. PEN bound to and activated GPR83, a G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptor (GPCR). Reductio...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Signal |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147544/ https://ncbi.nlm.nih.gov/pubmed/27117253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad0694 |
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