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Elevated NEFA levels impair glucose effectiveness by increasing net hepatic glycogenolysis
AIMS/HYPOTHESIS: Acute hyperglycaemia rapidly suppresses endogenous glucose production (EGP) in non-diabetic individuals, mainly by inhibiting glycogenolysis. Loss of this ‘glucose effectiveness’ contributes to fasting hyperglycaemia in type 2 diabetes. Elevated NEFA levels characteristic of type 2...
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| Pubblicato in: | Diabetologia |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317075/ https://ncbi.nlm.nih.gov/pubmed/22847060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2662-6 |
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