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Inhibiting gluconeogenesis prevents fatty acid-induced increases in endogenous glucose production

Glucose effectiveness, the ability of glucose per se to suppress endogenous glucose production (EGP), is lost in type 2 diabetes mellitus (T2DM). Free fatty acids (FFA) may contribute to this loss of glucose effectiveness in T2DM by increasing gluconeogenesis (GNG) and impairing the response to hype...

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Detalhes bibliográficos
Main Authors: Kehlenbrink, Sylvia, Tonelli, Julia, Koppaka, Sudha, Chandramouli, Visvanathan, Hawkins, Meredith, Kishore, Preeti
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711655/
https://ncbi.nlm.nih.gov/pubmed/19417129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00001.2009
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