Elevated NEFA levels impair glucose effectiveness by increasing net hepatic glycogenolysis

AIMS/HYPOTHESIS: Acute hyperglycaemia rapidly suppresses endogenous glucose production (EGP) in non-diabetic individuals, mainly by inhibiting glycogenolysis. Loss of this ‘glucose effectiveness’ contributes to fasting hyperglycaemia in type 2 diabetes. Elevated NEFA levels characteristic of type 2...

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Detaylı Bibliyografya
Yayımlandı:Diabetologia
Asıl Yazarlar: Kehlenbrink, S., Koppaka, S., Martin, M., Relwani, R., Cui, M.-H., Hwang, J.-H., Li, Y., Basu, R., Hawkins, M., Kishore, P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317075/
https://ncbi.nlm.nih.gov/pubmed/22847060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2662-6
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