Heteronemin Induces Anti-Proliferation in Cholangiocarcinoma Cells via Inhibiting TGF-β Pathway

A marine sesterterpenoid-type natural product, heteronemin, retains anticancer effects. In the current study, we investigate the antitumor mechanism of heteronemin in cholangiocarcinoma cells and further explore its molecular targets. Initially, heteronemin exhibited potent cytotoxic effects against...

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Detaylı Bibliyografya
Yayımlandı:Mar Drugs
Asıl Yazarlar: Lin, Hung-Yun, Tey, Shu-Leei, Ho, Yih, Chin, Yung-Tang, Wang, Kuan, Whang-Peng, Jacqueline, Shih, Ya-Jung, Chen, Yi-Ru, Yang, Yung-Ning, Chen, Yu-Cheng, Liu, Yi-Chang, Tang, Heng-Yuan, Yang, Yu-Chen SH
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316595/
https://ncbi.nlm.nih.gov/pubmed/30563284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120489
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