Heteronemin Induces Anti-Proliferation in Cholangiocarcinoma Cells via Inhibiting TGF-β Pathway

A marine sesterterpenoid-type natural product, heteronemin, retains anticancer effects. In the current study, we investigate the antitumor mechanism of heteronemin in cholangiocarcinoma cells and further explore its molecular targets. Initially, heteronemin exhibited potent cytotoxic effects against...

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Publicado no:Mar Drugs
Main Authors: Lin, Hung-Yun, Tey, Shu-Leei, Ho, Yih, Chin, Yung-Tang, Wang, Kuan, Whang-Peng, Jacqueline, Shih, Ya-Jung, Chen, Yi-Ru, Yang, Yung-Ning, Chen, Yu-Cheng, Liu, Yi-Chang, Tang, Heng-Yuan, Yang, Yu-Chen SH
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316595/
https://ncbi.nlm.nih.gov/pubmed/30563284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120489
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