Heteronemin Induces Anti-Proliferation in Cholangiocarcinoma Cells via Inhibiting TGF-β Pathway

A marine sesterterpenoid-type natural product, heteronemin, retains anticancer effects. In the current study, we investigate the antitumor mechanism of heteronemin in cholangiocarcinoma cells and further explore its molecular targets. Initially, heteronemin exhibited potent cytotoxic effects against...

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Publicat a:Mar Drugs
Autors principals: Lin, Hung-Yun, Tey, Shu-Leei, Ho, Yih, Chin, Yung-Tang, Wang, Kuan, Whang-Peng, Jacqueline, Shih, Ya-Jung, Chen, Yi-Ru, Yang, Yung-Ning, Chen, Yu-Cheng, Liu, Yi-Chang, Tang, Heng-Yuan, Yang, Yu-Chen SH
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316595/
https://ncbi.nlm.nih.gov/pubmed/30563284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120489
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