Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple DPYD Variants

DPYD genotyping prior to fluoropyrimidine treatment is increasingly implemented in clinical care. Without phasing information (i.e., allelic location of variants), current genotype-based dosing guidelines cannot be applied to patients carrying multiple DPYD variants. The primary aim of this study is...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes (Basel)
Prif Awduron: Lunenburg, Carin A. T. C., Henricks, Linda M., van Kuilenburg, André B. P., Mathijssen, Ron H. J., Schellens, Jan H. M., Gelderblom, Hans, Guchelaar, Henk-Jan, Swen, Jesse J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316498/
https://ncbi.nlm.nih.gov/pubmed/30487465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9120585
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