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Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws

Drug discovery frequently relies on the kinetic analysis of physicochemical reactions that are at the origin of the disease state. Amyloid fibril formation has been extensively investigated in relation to prevalent and rare neurodegenerative diseases, but thus far no therapeutic solution has directl...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Silva, Alexandra, Sárkány, Zsuzsa, Fraga, Joana S., Taboada, Pablo, Macedo-Ribeiro, Sandra, Martins, Pedro M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316134/
https://ncbi.nlm.nih.gov/pubmed/30287796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8040108
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