SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

The role of stress-induced increases in SUMO2/3 conjugation during the heat shock response (HSR) has remained enigmatic. We investigated SUMO signal transduction at the proteomic and functional level during the HSR in cells depleted of proteostasis network components via chronic heat shock factor 1...

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Publicado en:Cell Rep
Main Authors: Liebelt, Frauke, Sebastian, Rebecca M., Moore, Christopher L., Mulder, Monique P.C., Ovaa, Huib, Shoulders, Matthew D., Vertegaal, Alfred C.O.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316133/
https://ncbi.nlm.nih.gov/pubmed/30605679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.027
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