Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells

Autophagy occurs at a basal level in all eukaryotic cells and may support cell survival or activate death pathways. Due to its pathophysiologic significance, the autophagic machinery is a promising target for the development of multiple approaches for anti-neoplastic agents. We have recently describ...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zecchini, Silvia, Proietti Serafini, Francesca, Catalani, Elisabetta, Giovarelli, Matteo, Coazzoli, Marco, Di Renzo, Ilaria, De Palma, Clara, Perrotta, Cristiana, Clementi, Emilio, Buonanno, Federico, Ortenzi, Claudio, Marcantoni, Enrico, Taddei, Anna Rita, Picchietti, Simona, Fausto, Anna Maria, Cervia, Davide
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315039/
https://ncbi.nlm.nih.gov/pubmed/30584259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1254-x
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