Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells

Autophagy occurs at a basal level in all eukaryotic cells and may support cell survival or activate death pathways. Due to its pathophysiologic significance, the autophagic machinery is a promising target for the development of multiple approaches for anti-neoplastic agents. We have recently describ...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Zecchini, Silvia, Proietti Serafini, Francesca, Catalani, Elisabetta, Giovarelli, Matteo, Coazzoli, Marco, Di Renzo, Ilaria, De Palma, Clara, Perrotta, Cristiana, Clementi, Emilio, Buonanno, Federico, Ortenzi, Claudio, Marcantoni, Enrico, Taddei, Anna Rita, Picchietti, Simona, Fausto, Anna Maria, Cervia, Davide
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315039/
https://ncbi.nlm.nih.gov/pubmed/30584259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1254-x
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