Llwytho...
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Identifying disease-associated missense mutations remains a challenge, especially in large-scale sequencing studies. Here we establish an experimentally and computationally integrated approach to investigate the functional impact of missense mutations in the context of the human interactome network...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Genet |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314957/ https://ncbi.nlm.nih.gov/pubmed/29892012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0130-z |
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