Regulation of Epithelial Injury and Bile Duct Obstruction by NLRP3 and IL-1R1 in Experimental Biliary Atresia

BACKGROUND & AIMS: Biliary atresia (BA) results from a neonatal inflammatory and fibrosing obstruction of bile ducts of unknown etiology. Although the innate immune system has been linked to virus-induced mechanism of disease, the role of the inflammasome-mediated epithelial injury remains large...

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Udgivet i:J Hepatol
Main Authors: Yang, Li, Mizuochi, Tatsuki, Shivakumar, Pranavkumar, Mourya, Reena, Luo, Zhenhua, Gutta, Sridevi, Bezerra, Jorge A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314850/
https://ncbi.nlm.nih.gov/pubmed/29886157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.05.038
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