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Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II

O-GlcNAcylation is a nutrient-responsive glycosylation that plays a pivotal role in transcriptional regulation. Human RNA polymerase II (Pol II) is extensively modified by O-linked N-acetylglucosamine (O-GlcNAc) on its unique C-terminal domain (CTD), which consists of 52 heptad repeats. One approach...

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Vydáno v:Biochemistry
Hlavní autoři: Lu, Lei, Fan, Dacheng, Hu, Chia-Wei, Worth, Matthew, Ma, Zhi-Xiong, Jiang, Jiaoyang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314847/
https://ncbi.nlm.nih.gov/pubmed/26807597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01280
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