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Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II
O-GlcNAcylation is a nutrient-responsive glycosylation that plays a pivotal role in transcriptional regulation. Human RNA polymerase II (Pol II) is extensively modified by O-linked N-acetylglucosamine (O-GlcNAc) on its unique C-terminal domain (CTD), which consists of 52 heptad repeats. One approach...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314847/ https://ncbi.nlm.nih.gov/pubmed/26807597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01280 |
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