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Deciphering the Functions of Protein O-GlcNAcylation with Chemistry
O-GlcNAcylation is the modification of serine and threonine residues with β-N-acetylglucosamine (O-GlcNAc) on intracellular proteins. This dynamic modification is attached by O-GlcNAc transferase (OGT) and removed by O-GlcNAcase (OGA) and is a critical regulator of various cellular processes. Furthe...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8210773/ https://ncbi.nlm.nih.gov/pubmed/28055183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01065 |
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