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Genetic and structural insights into broad neutralization of hepatitis C virus by human V(H)1-69 antibodies
An effective vaccine to the antigenically diverse hepatitis C virus (HCV) must target conserved immune epitopes. Here, we investigate cross-neutralization of HCV genotypes by broadly neutralizing antibodies (bNAbs) encoded by the relatively abundant human gene family V(H)1-69. We have deciphered the...
Shranjeno v:
| izdano v: | Sci Adv |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Association for the Advancement of Science
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314831/ https://ncbi.nlm.nih.gov/pubmed/30613781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav1882 |
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