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V(H)1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design

Broadly neutralizing antibodies (bnAbs) are potential therapeutic molecules and valuable tools for studying conserved viral targets for vaccine and drug design. Interestingly, antibody responses to conserved epitopes can be highly convergent at the molecular level. Human antibodies targeting a numbe...

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Detalles Bibliográficos
Publicado en:Curr Opin Virol
Main Authors: Chen, Fang, Tzarum, Netanel, Wilson, Ian A, Law, Mansun
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266006/
https://ncbi.nlm.nih.gov/pubmed/30884330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2019.02.004
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