miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis

Inflammation often induces regeneration to repair the tissue damage. However, chronic inflammation can transform temporary hyperplasia into a fertile ground for tumorigenesis. Here, we demonstrate that the microRNA miR-34a acts as a central safeguard to protect the inflammatory stem cell niche and r...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Wang, Lihua, Wang, Ergang, Wang, Yi, Mines, Robert, Xiang, Kun, Sun, Zhiguo, Zhou, Gaiting, Chen, Kai-Yuan, Rakhilin, Nikolai, Chao, Shanshan, Ye, Gaoqi, Wu, Zhenzhen, Yan, Huiwen, Shen, Hong, Everitt, Jeffrey, Bu, Pengcheng, Shen, Xiling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2018
Onderwerpen:
Cancer Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314783/
https://ncbi.nlm.nih.gov/pubmed/30543324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39479
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