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Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

Axonal transport is required for neuronal development and survival. Transport from the axon to the soma is driven by the molecular motor cytoplasmic dynein, yet it remains unclear how dynein is spatially and temporally regulated. We find that the dynein effector Hook1 mediates transport of TrkB–BDNF...

詳細記述

保存先:
書誌詳細
出版年:J Cell Biol
主要な著者: Olenick, Mara A., Dominguez, Roberto, Holzbaur, Erika L.F.
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314548/
https://ncbi.nlm.nih.gov/pubmed/30373907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201805016
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