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Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons
Axonal transport is required for neuronal development and survival. Transport from the axon to the soma is driven by the molecular motor cytoplasmic dynein, yet it remains unclear how dynein is spatially and temporally regulated. We find that the dynein effector Hook1 mediates transport of TrkB–BDNF...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Rockefeller University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314548/ https://ncbi.nlm.nih.gov/pubmed/30373907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201805016 |
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