A hotspot for disease-associated variants of human PGM1 is associated with impaired ligand binding and loop dynamics

Lignende værker

• Asp263 missense variants perturb the active site of human phosphoglucomutase 1 (PGM1)
  af: Stiers, Kyle M., et al.
  Udgivet: (2017)
• Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1
  af: Muenks, Andrew G., et al.
  Udgivet: (2017)
• Compromised Catalysis and Potential Folding Defects in in Vitro Studies of Missense Mutants Associated with Hereditary Phosphoglucomutase 1 Deficiency
  af: Lee, Yingying, et al.
  Udgivet: (2014)
• Structural and dynamical description of the enzymatic reaction of a phosphohexomutase
  af: Stiers, Kyle M., et al.
  Udgivet: (2019)
• Biology, mechanism, and structure of enzymes in the α-D-phosphohexomutase superfamily
  af: Stiers, Kyle M., et al.
  Udgivet: (2017)