Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry

Lysophosphatidic acid (LPA) activates cognate G protein-coupled receptors (GPCRs) to initiate biological signaling cascades. Lysophospholipid (LP) receptor binding properties remain incompletely assessed because of difficulties with ligand lipophilicity and lipid “stickiness.” These inherent attribu...

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Bibliografiska uppgifter
I publikationen:J Lipid Res
Huvudupphovsmän: Mizuno, Hirotaka, Kihara, Yasuyuki, Kussrow, Amanda, Chen, Allison, Ray, Manisha, Rivera, Richard, Bornhop, Darryl J., Chun, Jerold
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Methods
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314248/
https://ncbi.nlm.nih.gov/pubmed/30463988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D089938
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