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Quantitation of Membrane-Ligand Interactions Using Backscattering Interferometry
Though membrane-associated proteins are ubiquitous within all living organisms and represent the majority of drug targets, a general method for direct, label-free measurement of ligand binding to native membranes has not been reported. Here we show backscattering interferometry (BSI) to be a viable...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246389/ https://ncbi.nlm.nih.gov/pubmed/21399645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1790 |
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