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Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding
BACKGROUND: Lysophosphatidic acid (LPA) is a bioactive lysophospholipid that acts through its six cognate G protein-coupled receptors. As a family, lysophospholipids have already produced medicines (e.g., sphingosine 1-phosphate) as is being pursued for LPA through the use of specific antibodies tha...
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| Publicado en: | Lipids Health Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8048308/ https://ncbi.nlm.nih.gov/pubmed/33853612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-021-01454-4 |
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