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Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding
BACKGROUND: Lysophosphatidic acid (LPA) is a bioactive lysophospholipid that acts through its six cognate G protein-coupled receptors. As a family, lysophospholipids have already produced medicines (e.g., sphingosine 1-phosphate) as is being pursued for LPA through the use of specific antibodies tha...
保存先:
| 出版年: | Lipids Health Dis |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8048308/ https://ncbi.nlm.nih.gov/pubmed/33853612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-021-01454-4 |
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