Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees

Genotype imputation is widely used in genome-wide association studies to boost variant density, allowing increased power in association testing. Many studies currently include pedigree data due to increasing interest in rare variants coupled with the availability of appropriate analysis tools. The p...

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Опубликовано в: :Genome Res
Главные авторы: Ullah, Ehsan, Mall, Raghvendra, Abbas, Mostafa M., Kunji, Khalid, Nato, Alejandro Q., Bensmail, Halima, Wijsman, Ellen M., Saad, Mohamad
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314157/
https://ncbi.nlm.nih.gov/pubmed/30514702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.236315.118
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