Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees

Genotype imputation is widely used in genome-wide association studies to boost variant density, allowing increased power in association testing. Many studies currently include pedigree data due to increasing interest in rare variants coupled with the availability of appropriate analysis tools. The p...

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Udgivet i:Genome Res
Main Authors: Ullah, Ehsan, Mall, Raghvendra, Abbas, Mostafa M., Kunji, Khalid, Nato, Alejandro Q., Bensmail, Halima, Wijsman, Ellen M., Saad, Mohamad
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314157/
https://ncbi.nlm.nih.gov/pubmed/30514702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.236315.118
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