The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea

In multicellular organisms, cell type diversity and fate depend on specific sets of transcript isoforms generated by post-transcriptional RNA processing. Here, we used Schmidtea mediterranea, a flatworm with extraordinary regenerative abilities and a large pool of adult stem cells, as an in vivo mod...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Schmidt, David, Reuter, Hanna, Hüttner, Katja, Ruhe, Larissa, Rabert, Franziska, Seebeck, Florian, Irimia, Manuel, Solana, Jordi, Bartscherer, Kerstin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312358/
https://ncbi.nlm.nih.gov/pubmed/30557303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007828
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