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The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea

In multicellular organisms, cell type diversity and fate depend on specific sets of transcript isoforms generated by post-transcriptional RNA processing. Here, we used Schmidtea mediterranea, a flatworm with extraordinary regenerative abilities and a large pool of adult stem cells, as an in vivo mod...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Schmidt, David, Reuter, Hanna, Hüttner, Katja, Ruhe, Larissa, Rabert, Franziska, Seebeck, Florian, Irimia, Manuel, Solana, Jordi, Bartscherer, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312358/
https://ncbi.nlm.nih.gov/pubmed/30557303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007828
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