The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea

In multicellular organisms, cell type diversity and fate depend on specific sets of transcript isoforms generated by post-transcriptional RNA processing. Here, we used Schmidtea mediterranea, a flatworm with extraordinary regenerative abilities and a large pool of adult stem cells, as an in vivo mod...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Schmidt, David, Reuter, Hanna, Hüttner, Katja, Ruhe, Larissa, Rabert, Franziska, Seebeck, Florian, Irimia, Manuel, Solana, Jordi, Bartscherer, Kerstin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312358/
https://ncbi.nlm.nih.gov/pubmed/30557303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007828
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