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Trichloroethene metabolite dichloroacetyl chloride induces apoptosis and compromises phagocytosis in Kupffer Cells: Activation of inflammasome and MAPKs

Exposure to trichloroethene (TCE), an occupational and ubiquitous environmental contaminant, is associated with the development of several autoimmune diseases, including autoimmune hepatitis (AIH). However, mechanisms contributing to TCE-mediated AIH are not known. Earlier, we have shown that dichlo...

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Publicat a:PLoS One
Autors principals: Wang, Hui, Wang, Gangduo, Ansari, G. A. Shakeel, Khan, M. Firoze
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312261/
https://ncbi.nlm.nih.gov/pubmed/30596806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210200
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