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Redox regulation of hepatic NLRP3 inflammasome activation and immune dysregulation in Trichloroethene-mediated autoimmunity

Trichloroethene (TCE) exposure is associated with the development of various autoimmune diseases (ADs), including autoimmune hepatitis (AIH) and systemic lupus erythematosus (SLE), potentially through the generation of excessive reactive oxygen and nitrogen species (RONS; oxidative stress). However,...

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Publicado en:Free Radic Biol Med
Autores principales: Wang, Hui, Wang, Gangduo, Liang, Yuejin, Du, Xiaotang, Boor, Paul J., Sun, Jiaren, Khan, M. Firoze
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848782/
https://ncbi.nlm.nih.gov/pubmed/31419475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.08.014
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