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Trichloroethene metabolite dichloroacetyl chloride induces apoptosis and compromises phagocytosis in Kupffer Cells: Activation of inflammasome and MAPKs

Exposure to trichloroethene (TCE), an occupational and ubiquitous environmental contaminant, is associated with the development of several autoimmune diseases, including autoimmune hepatitis (AIH). However, mechanisms contributing to TCE-mediated AIH are not known. Earlier, we have shown that dichlo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Hui, Wang, Gangduo, Ansari, G. A. Shakeel, Khan, M. Firoze
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312261/
https://ncbi.nlm.nih.gov/pubmed/30596806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210200
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