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Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin

Although the study of pathogen sensing by host defense systems continues to uncover a role for inflammasome components specific to particular pathogens, gaps remain in our knowledge. After internalization, Francisella escapes from the phagosome in mononuclear cells and is thought to be detected by i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mitra, Srabani, Dolvin, Erin, Krishnamurthy, Karthikeyan, Wewers, Mark D., Sarkar, Anasuya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312237/
https://ncbi.nlm.nih.gov/pubmed/30596757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209931
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