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Pyrin Critical to Macrophage IL-1β Response to Francisella Challenge()

Relative to monocytes, human macrophages are deficient in their ability to process and release IL-1β. In an effort to explain this difference, we used a model of IL-1β processing and release that is dependent upon bacterial escape into the cytosol. Fresh human blood monocytes were compared with mono...

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Bibliografiska uppgifter
Huvudupphovsmän: Gavrilin, Mikhail A., Mitra, Srabani, Seshadri, Sudarshan, Nateri, Jyotsna, Berhe, Freweine, Hall, Mark W., Wewers, Mark D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964683/
https://ncbi.nlm.nih.gov/pubmed/19494323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803073
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