Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury

Lung endothelial cell apoptosis and injury occur throughout all stages of acute lung injury/acute respiratory distress syndrome and impact disease progression. Caspases 1, 4, and 5 are essential for completion of the apoptotic program known as pyroptosis that also involves proinflammatory cytokines....

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Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Mitra, Srabani, Exline, Matthew, Habyarimana, Fabien, Gavrilin, Mikhail A., Baker, Paul J., Masters, Seth L., Wewers, Mark D., Sarkar, Anasuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2018
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039876/
https://ncbi.nlm.nih.gov/pubmed/29365280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0393OC
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