GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice

Ischemic stroke triggers an elevation in tonic GABA inhibition that impairs the ability of the brain to form new structural and functional cortical circuits required for recovery. This stroke-induced increase in tonic inhibition is caused by impaired GABA uptake via the glial GABA transporter GAT3,...

Full description

Saved in:
Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Lie, Maria EK, Gowing, Emma K, Johansen, Nina B, Dalby, Nils Ole, Thiesen, Louise, Wellendorph, Petrine, Clarkson, Andrew N
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311676/
https://ncbi.nlm.nih.gov/pubmed/29160736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17744123
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items