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GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice

Ischemic stroke triggers an elevation in tonic GABA inhibition that impairs the ability of the brain to form new structural and functional cortical circuits required for recovery. This stroke-induced increase in tonic inhibition is caused by impaired GABA uptake via the glial GABA transporter GAT3,...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Lie, Maria EK, Gowing, Emma K, Johansen, Nina B, Dalby, Nils Ole, Thiesen, Louise, Wellendorph, Petrine, Clarkson, Andrew N
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311676/
https://ncbi.nlm.nih.gov/pubmed/29160736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17744123
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