Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate

Emerging evidence has shown that the hepatocyte growth factor (HGF) and its receptor, MET proto-oncogene, receptor tyrosine kinase (MET), promote cell proliferation, motility, morphogenesis, and angiogenesis. Whereas up-regulation of MET expression has been observed in aggressive and metastatic pros...

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Vydáno v:J Biol Chem
Hlavní autoři: Mi, Jiaqi, Hooker, Erika, Balog, Steven, Zeng, Hong, Johnson, Daniel T., He, Yongfeng, Yu, Eun-Jeong, Wu, Huiqing, Le, Vien, Lee, Dong-Hoon, Aldahl, Joseph, Gonzalgo, Mark L., Sun, Zijie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311521/
https://ncbi.nlm.nih.gov/pubmed/30401749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005395
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