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Accessibility of the Shine-Dalgarno Sequence Dictates N-Terminal Codon Bias in E. coli
Despite considerable efforts, no physical mechanism has been shown to explain N-terminal codon bias in prokaryotic genomes. Using a systematic study of synonymous substitutions in two endogenous E. coli genes, we show that interactions between the coding region and the upstream Shine-Dalgarno (SD) s...
Shranjeno v:
| izdano v: | Mol Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311106/ https://ncbi.nlm.nih.gov/pubmed/29883608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.008 |
| Oznake: |
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