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Shine–Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG
During translation, usually only one in ≈400 misincorporations affects the function of a nascent protein, because only chemically similar near-cognate amino acids are misincorporated in place of the cognate one. The deleterious misincorporation of a chemically dissimilar noncognate amino acid during...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504839/ https://ncbi.nlm.nih.gov/pubmed/18667704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801974105 |
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