Shine–Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG

During translation, usually only one in ≈400 misincorporations affects the function of a nascent protein, because only chemically similar near-cognate amino acids are misincorporated in place of the cognate one. The deleterious misincorporation of a chemically dissimilar noncognate amino acid during...

Full description

Saved in:
Bibliographic Details
Main Authors: Di Giacco, Viviana, Márquez, Viter, Qin, Yan, Pech, Markus, Triana-Alonso, Francisco J., Wilson, Daniel N., Nierhaus, Knud H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504839/
https://ncbi.nlm.nih.gov/pubmed/18667704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801974105
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items