Prednisone Pharmacokinetics during Pregnancy and Lactation

To evaluate the steady-state pharmacokinetics of prednisone and its metabolite prednisolone in pregnant and lactating female subjects, nineteen subjects received prednisone (4–40 mg/day orally) in early- (n=3), mid- (n=9) and late- (n=13) pregnancy as well as postpartum with (n=2) and without (n=5)...

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Gepubliceerd in:J Clin Pharmacol
Hoofdauteurs: Ryu, Rachel J., Easterling, Thomas R., Caritis, Steve N., Venkataramanan, Raman, Umans, Jason G., Ahmed, Mahmoud S., Clark, Shannon, Kantrowitz-Gordon, Ira, Hays, Karen, Bennett, Brooke, Honaker, Matthew T., Thummel, Kenneth E., Shen, Danny D., Hebert, Mary F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310475/
https://ncbi.nlm.nih.gov/pubmed/29733485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1122
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