Pharmacokinetics of Oseltamivir Among Pregnant and Non-pregnant Women

OBJECTIVE: To delineate the pharmacokinetics of oseltamivir and its active metabolite oseltamivir carboxylate during pregnancy. Physiologic changes of pregnancy, including increased renal filtration and secretion, may increase the clearance of oseltamivir carboxylate. STUDY DESIGN: Sixteen pregnant...

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Main Authors: Beigi, Richard H., Han, Kelong, Venkataramanan, Raman, Hankins, Gary D., Clark, Shannon, Hebert, Mary F., Easterling, Thomas, Zajicek, Anne, Ren, Zhaoxia, Mattison, Donald R., Caritis, Steve N.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111757/
https://ncbi.nlm.nih.gov/pubmed/21492826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2011.03.002
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