Safety and Pharmacokinetics of Pravastatin Used for the Prevention of Preeclampsia in High-Risk Pregnant Women: A Pilot Randomized Controlled Trial

BACKGROUND: Preeclampsia complicates approximately 3% to 5% of pregnancies and remains a major cause of maternal and neonatal morbidity and mortality. It shares pathogenic similarities with adult cardiovascular disease as well as many risk factors. Pravastatin, a hydrophilic, 3-hydroxy-3-methyl-glut...

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Publicat a:Am J Obstet Gynecol
Autors principals: Costantine, Maged M., Cleary, Kirsten, Hebert, Mary F., Ahmed, Mahmoud S., Brown, Linda M., Ren, Zhaoxia, Easterling, Thomas R., Haas, David M., Haneline, Laura S., Caritis, Steve N., Venkataramanan, Raman, West, Holly, D’Alton, Mary, Hankins, Gary
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884459/
https://ncbi.nlm.nih.gov/pubmed/26723196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2015.12.038
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