Safety and Pharmacokinetics of Pravastatin Used for the Prevention of Preeclampsia in High-Risk Pregnant Women: A Pilot Randomized Controlled Trial

BACKGROUND: Preeclampsia complicates approximately 3% to 5% of pregnancies and remains a major cause of maternal and neonatal morbidity and mortality. It shares pathogenic similarities with adult cardiovascular disease as well as many risk factors. Pravastatin, a hydrophilic, 3-hydroxy-3-methyl-glut...

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Detalhes bibliográficos
Publicado no:Am J Obstet Gynecol
Main Authors: Costantine, Maged M., Cleary, Kirsten, Hebert, Mary F., Ahmed, Mahmoud S., Brown, Linda M., Ren, Zhaoxia, Easterling, Thomas R., Haas, David M., Haneline, Laura S., Caritis, Steve N., Venkataramanan, Raman, West, Holly, D’Alton, Mary, Hankins, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884459/
https://ncbi.nlm.nih.gov/pubmed/26723196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2015.12.038
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