Safety and Pharmacokinetics of Pravastatin Used for the Prevention of Preeclampsia in High-Risk Pregnant Women: A Pilot Randomized Controlled Trial

BACKGROUND: Preeclampsia complicates approximately 3% to 5% of pregnancies and remains a major cause of maternal and neonatal morbidity and mortality. It shares pathogenic similarities with adult cardiovascular disease as well as many risk factors. Pravastatin, a hydrophilic, 3-hydroxy-3-methyl-glut...

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Veröffentlicht in:Am J Obstet Gynecol
Hauptverfasser: Costantine, Maged M., Cleary, Kirsten, Hebert, Mary F., Ahmed, Mahmoud S., Brown, Linda M., Ren, Zhaoxia, Easterling, Thomas R., Haas, David M., Haneline, Laura S., Caritis, Steve N., Venkataramanan, Raman, West, Holly, D’Alton, Mary, Hankins, Gary
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884459/
https://ncbi.nlm.nih.gov/pubmed/26723196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2015.12.038
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