Pharmacokinetics of Metoprolol During Pregnancy and Lactation

The objective of this study was to evaluate the steady-state pharmacokinetics of metoprolol during pregnancy and lactation. Serial plasma, urine, and breast milk concentrations of metoprolol and its metabolite, α-hydroxymetoprolol, were measured over 1 dosing interval in women treated with metoprolo...

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Bibliografiske detaljer
Udgivet i:J Clin Pharmacol
Main Authors: Ryu, Rachel J., Eyal, Sara, Easterling, Thomas R., Caritis, Steve N., Venkataraman, Raman, Hankins, Gary, Rytting, Erik, Thummel, Kenneth, Kelly, Edward J., Risler, Linda, Phillips, Brian, Honaker, Matthew T., Shen, Danny D., Hebert, Mary F.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564514/
https://ncbi.nlm.nih.gov/pubmed/26461463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.631
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