Targeting NAD(+) metabolism to enhance radiation therapy responses

NAD(+) metabolism is integrally connected with the mechanisms of action of radiation therapy and is altered in many radiation-resistant tumors. This makes NAD(+) metabolism an ideal target for therapies that increase radiation sensitivity and improve patient outcomes. This review provides an overvie...

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Publicado en:Semin Radiat Oncol
Main Authors: Lewis, Joshua E., Singh, Naveen, Holmila, Reetta J., Sumer, Baran D., Williams, Noelle S., Furdui, Cristina M., Kemp, Melissa L., Boothman, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310039/
https://ncbi.nlm.nih.gov/pubmed/30573185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semradonc.2018.10.009
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