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MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer

Head and Neck Squamous Cell Cancer (HNSCC) presents with multiple treatment challenges limiting overall survival rates and affecting patients' quality of life. Amongst these, resistance to radiation therapy constitutes a major clinical problem in HNSCC patients compounded by origin, location, a...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Shukla, Kirtikar, Singh, Naveen, Lewis, Joshua E., Tsang, Allen W., Boothman, David A., Kemp, Melissa L., Furdui, Cristina M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685994/
https://ncbi.nlm.nih.gov/pubmed/33262939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.536377
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