MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer

Head and Neck Squamous Cell Cancer (HNSCC) presents with multiple treatment challenges limiting overall survival rates and affecting patients' quality of life. Amongst these, resistance to radiation therapy constitutes a major clinical problem in HNSCC patients compounded by origin, location, a...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Shukla, Kirtikar, Singh, Naveen, Lewis, Joshua E., Tsang, Allen W., Boothman, David A., Kemp, Melissa L., Furdui, Cristina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685994/
https://ncbi.nlm.nih.gov/pubmed/33262939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.536377
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